Publications

---

Original research papers

• Mitrović J. R., Bjelošević Žiberna M., Vukadinović A., Knutson D. E., Sharmin D., Kremenović A., Ahlin Grabnar P., Planinšek O., Lunter D., Cook J. M., Savić M. M., Savić S. D.. . Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study. European Journal of Pharmaceutical Sciences. 2023; 189: 106557. (Q1; M21 Pharmaceutics, IF 4.6) https://doi.org/10.1016/j.ejps.2023.106557

• Mitrović J. R., Divović Matović B., Knutson D. E., Petković M., Djorovic Dj., Randjelović D. V., Dobričić V. D., Đoković J. B., Lunter D. J., Cook J. M., Savić M. M., Savić S. D.. High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances. International Journal of Pharmaceutics. 2023; 122613.(Q1; M21 Pharmaceutics, IF 6.51) https://doi.org/10.1016/j.ijpharm.2023.122613

• Ilić T, Đoković JB, Nikolić I, Mitrović JR, Pantelić I, Savić SD, Savić MM. Parenteral Lipid-Based Nanoparticles for CNS Disorders: Integrating Various Facets of Preclinical Evaluation towards More Effective Clinical Translation. Pharmaceutics. 2023; 15(2):443.(Q1; M21 Pharmaceutics, IF 6.525) https://doi.org/10.3390/pharmaceutics15020443

• Divović Matović B, Knutson D, Mitrović J, Stevanović V, Stanojević B, Savić S, Cook J, Savić M. Behavioural interaction of pyrazoloquinolinone positive allosteric modulators at α6GABAA receptors and diazepam in rats: Anti-diazepam-induced ataxia action as a structure-dependent feature. Basic & Clinical Pharmacology & Toxicology. 2022; 1-11. (Q2; M22 Pharmacology & Pharmacy, IF 3.688) https://doi.org/10.1111/bcpt.13801

• Đoković JB, Demisli S, Savić SM, Marković BD, Cekić ND, Randjelovic DV, Mitrović JR, Lunter DJ, Papadimitriou V, Xenakis A, Savić SD. The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions. Pharmaceutics. 2022 Aug 10;14(8):1666. (Q1; M21 Pharmaceutics, IF 6.525) https://doi.org/10.3390/pharmaceutics14081666

• Bernardo, A., Lee, P., Marcotte, M., Mian, M.Y., Rezvanian, S., Sharmin, D., Kovačević, A., Savić, M.M., Cook, J.M., Sibille, E. and Prevot, T.D., 2022. Symptomatic and neurotrophic effects of GABAA receptor positive allosteric modulation in a mouse model of chronic stress. Neuropsychopharmacology, pp.1-12. (Q1; M21a Pharmacology & Pharmacy, IF 8.294) https://doi.org/10.1038/s41386-022-01360-y

     

Conference poster presentations

• Preformulation and development of preliminary nanoemulsion carrier for patent protected compound GL-II-73

  Autori: Đoković, Jelena; Marković, Bojan; Sharmin, Dishary; Cook, James M; Savić, Miroslav; Savić, Snežana

  14th Central European Symposium on Pharmaceutical Technology, 28 - 30 September 2023, Ohrid, North Macedonia

• Design of tailor-made biocompatible nanocarrier for novel pyrazoloquinolinone ligand (CW-02-79) based on comprehensive evaluation of critical physicochemical descriptors

  Autori: Stanković, Tijana; Ilić, Tanja; Pantelić, Ivana; Tošić, Anđela; Mitrović, Jelena; Cook, James M; Savić, Miroslav; Savić, Snežana

  10th IAPC Meeting. Tenth World Conference on Physico-Chemical Methods in Drug Discovery & Sixth World Conference on ADMET and DMPK, 4 - 6 September 2023, Belgrade, Serbia

• Searching for the best way to incorporate the proprietary compound GL-II -73 into the nanoemulsion carrier for prospective parenteral application

  Autori: Đoković, Jelena; Marković, Bojan; Sharmin, Dishary; Cook, James M; Savić, Miroslav; Savić, Snežana

  10th IAPC Meeting. Tenth World Conference on Physico-Chemical Methods in Drug Discovery & Sixth World Conference on ADMET and DMPK, 4 - 6 September 2023, Belgrade, Serbia

• Navigating towards improved cytotoxicity assessment in nanomedicine development: Shifting from colorimetric to fluorescence-based assays

  Autori: Nikolić, Ines; Petrović, Marija; Mitrović, Jelena; Sublet, Emmanuelle; Jordan, Olivier; Savić, Snežana; Borchard, Gerrit

  10th IAPC Meeting. Tenth World Conference on Physico-Chemical Methods in Drug Discovery & Sixth World Conference on ADMET and DMPK, 4 - 6 September 2023, Belgrade, Serbia

• Neuropharmacokinetics: the secret life of - old and novel - psychopharmacological drugs

  Autori: Savić, Miroslav

  10th IAPC Meeting. Tenth World Conference on Physico-Chemical Methods in Drug Discovery & Sixth World Conference on ADMET and DMPK, 4 - 6 September 2023, Belgrade, Serbia

• Sizing experiments and bio-nano interactions: method matters

  Authors: Nikolić, Ines; Petrović, Marija; Krupnik, Leonard; Randjelovic, Danijela; Avaro, Jonathan; Neels, Antonia; Borhard, Gerrit; Jordan, Olivier; Đoković, Jelena; Savić, Snežana

  4th European Conference on Pharmaceutics, 20 - 21 March 2023, Marseille, France

• Biocompatible nanoemulsions as a tool for preclinical testing of CW-02-79, a pyrazoloquinolinone modulator of sigma-2 receptors: preformulation and formulation studies

  Authors: Ilić, Tanja; Stanković, Tijana; Mitrović, Jelena; Pantelić, Ivana; Dobričić, Vladimir; Cook, James M.; Savić, Miroslav; Savić, Snežana

  4th European Conference on Pharmaceutics, 20 - 21 March 2023, Marseille, France

• Structural analysis of PEGylated nanoemulsions using EPR spectroscopy – the impact of an active compound incorporated in stabilizing layer

  Authors: Đoković, Jelena; Demisli, Sotiria; Papadimitriou, Vassiliki; Savić, Snežana

  4th European Conference on Pharmaceutics, 20 - 21 March 2023, Marseille, France

• Neuroimmune aspects of mood, anxiety and cognitive effects of leads/drug candidates acting at GABAA and/or sigma-2 receptors: In vitro/in vivo delineation by nano- and hiPSC-based platforms - presentation

  Authors: Savić, Snežana; Pantelić, Ivana; Jančić, Ivan; Savić, Miroslav

  8th Congress of Pharmacists of Serbia, 12.-15. October 2022, Belgrade, Serbia

• Investigation of albumin adsorption on DK-I-56-1 nanocrystals by dynamic light scattering

  Authors: Mitrović, Jelena; Knutson, Daniel; Nikolić, Ines; Cook, James; Savić, Miroslav; Savić, Snežana

  8th Congress of Pharmacists of Serbia, 12.-15. October 2022, Belgrade, Serbia

• Analyzing the impact of the oil phase selection and curcumin presence on the nanoemulsion stabilizing layer using electron paramagnetic resonance spectroscopy

  Authors: Đoković, Jelena; Demisli, Sotiria; Papadimitriou, Vassiliki; Xenakis, Aristotelis; Savić, Snežana

  8th Congress of Pharmacists of Serbia, 12.-15. October 2022, Belgrade, Serbia

• A proposal of innovative injectability assessment method for intravenous formulations - case study on PEGylated nanoemulsions

  Authors: Đoković, Jelena; Savić, Sanela; Cekić, Nebojša; Savić, Snežana

  9th BBBB International conference on pharmaceutical sciences, 15 - 17 September 2022, Ljubljana, Slovenia

• Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1); process parameters and cryoprotectant selection through stability study

  Authors: Mitrović, Jelena; Bjelošević, Maja; Knutson, Daniel E.; Kremenović, Aleksandar; Lunter, Dominique; Ahlin Grabnar, Pegi; Cook, James M.; Savić, Miroslav M.; Savić, Snežana D.

  9th BBBB International conference on pharmaceutical sciences, 15 - 17 September 2022, Ljubljana, Slovenia

• Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3

  Authors: Mitrović, Jelena; Petković, Miloš; Ranđelović, Danijela; Đoković, Jelena; Knutson, Daniel; Cook, James; Savić, Vladimir; Savić, Miroslav; Savić, Snežana

  13th World meeting on pharmaceutics, biopharmaceutics and pharmaceutical technology, 28-31 March 2022, Rotterdam, Netherlands

© 2022 Faculty of Pharmacy. All rights reserved.